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Theoretical considerations suggest fat loss effects should continue as long as the compound is administered, since the mechanism (beta-3 adrenergic lipolysis, lipogenesis inhibition) does not involve receptor desensitization in the way that some hormonal pathways do

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This product is not a drug, dietary supplement, or food product as defined under the Federal Food, Drug, and Cosmetic Act

Testing for variants in the genes that encode TPMT and nudix hydrolase 15 (NUDT15), another enzyme involved in thiopurine metabolism, may be useful to identify patients at risk of myelotoxicity and intolerance

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