However, in another study reporting administration of NR or the CD38 inhibitor GSK987A to mdx mice for 20 weeks 267 , treated mice with the CD38 inhibitor showed increased NAD + levels in muscle tissue, but no improvement was found in muscle function after treatment with either the inhibitor or with NR
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In concomitant with the previous results, ROS generation may be a radical factor underlying TBT toxicity
Typically, the medication dose increases slowly over 16 to 20 weeks
