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That decline is one reason researchers started studying GHK-Cu in the first place

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Dose and rate matter (e.g., magnesium given too quickly may cause flushing or low blood pressure)

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Because depleted glutathione impairs mitochondrial function and burdens the liver, the therapy is frequently paired with care for stubborn weight gain that has not responded to diet and exercise alone, supporting detoxification and metabolic efficiency rather than acting as a weight loss drug

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