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A systematic review and meta-analysis of randomized controlled trials found that probiotics reduced whole-gut transit time by roughly 12.4 hours and increased stool frequency by about 1.3 bowel movements per week compared with placebo, with Bifidobacterium lactis strains showing the clearest benefit

FAs may also increase uric acid levels by inhibiting the excretion process

Increase intake gradually to avoid bloating, and ensure adequate fluid intake

Within this framework, men with persistently low serum testosterone levels may exhibit diminished anabolic capacity and therefore increased susceptibility to muscle loss during periods of substantial weight reduction

GSTO-1 is member of Phase II enzymes that catalyze glutathione-dependent antioxidant pathways (Fig 1)