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Regulation of stem cell fate by ROS-mediated alteration of metabolism

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Co-administration of iRGD with sorafenib-loaded iron-based metal-organic framework as a targeted ferroptosis agent for liver cancer therapy

It is thus essential that intracellular heme is not allowed to exist in an unbound state and must either be bound to a chaperone molecule or be enclosed in intracellular membrane structures, for instance the endoplasmic reticulum