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Starting from the square-cube law equations [1] [2] , an equation for the change in brain volume proportional to the change in brain surface area [6] was derived

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For example, the combination of alcohol and barbiturates amplify the CNS depressant effect which is why it is easy to overdose on this combination

However, clinically successful treatment strategies are still lacking and are often inspired by treatment options for diseases with similar clinical presentations, such as ME/CFS