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J Pharmacol Exp Ther 303, 468475 (2002)

Common side effects include nausea, constipation, diarrhoea, reduced appetite, bloating, and indigestion

165 Atractylenolide I, a bioactive component of Atractylodes macrocephala , also showed suppression of intestinal inflammation via inhibition of the JNK/iNOS signaling pathway

Instead, it might help tolerate the medication better and boost energy production to reduce weakness and fatigue when taking a low-calorie diet with semaglutide