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First, as we have shown above in Figures4 and5, the sulfation reaction saturates at fairly low APAP doses because of the low concentration of PAPS

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This process seems to not only increase intercellular levels of Glutathione and precursors at the time of ingestion, but also builds up stores of these substances within the cells which lasts for a substantial post-ingestion time interval." Fidelus RK, Tsan MF