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Niacinamide Niacinamide is another ingredient widely used as part of a combination therapy for hyperpigmentation due to its skin-brightening and anti-inflammatory properties which lead to a lighter and more even skin tone 6

95% CI (24.28, 17.14) vs 2.77

doi: 10.1007/s00253-018-9226-8 5

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Publicly available TCGA data were accessed and analyzed using the GEPIA2 web at All other data generated in this study are available within the Article, Supplementary Information, or Source Data