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Introduction Interstitial cystitis/Painful bladder syndrome (IC/PBS) is chronic discomfort of the bladder wall, presenting with symptoms such as urinary frequency, urgency, and severe pelvic or suprapubic pain

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This study also observed an increase of Lachnoclostridium bolteae , the emergence of Enterobacter cloacae and the detection of resistance genes that were previously not detectable before antibiotic treatment 6