PMID 23303275
Most therapeutic compounds target a single pathway, but this peptide orchestrates a coordinated biological response through at least six distinct molecular routes
doi: 10.3389/fendo.2024.1396192 Received 05 March 2024 Accepted 14 May 2024 Published 30 May 2024 Volume 15 - 2024 Edited by Vittoria Rago, University of Calabria, Italy Reviewed by Xiaoqiang Wang, City of Hope, United States Jagpreet Singh Nanda, Cedars Sinai Medical Center, United States Updates Copyright 2024 Elemam, Hotait, Saleh, El-Huneidi and Talaat
Stereochemistry is preserved from the IUPAC descriptor (3S,6S,9R,12S,15S,23S), with position 4 of the cycle being D-phenylalanine
Structure of mitochondrial pyruvate carrier and its inhibition mechanism