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Under sustained reductions in nutrient inflow, metabolic reserve may narrow as reduced substrate availability limits mitochondrial redox regeneration and constrains the capacity to match oxidative flux with regenerative turnover

paracasei Stimulates Colonic Afferents Some, but not all GLP-1 immuno-labeled L-cells in the colonic epithelium of SD rats ( n = 4 rats, Figure 2A) expressed GLP-1Rs

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Since the cloning of the first OR, those models have been superseded by heterologous expression systems (HEK, CHO, COS-7, Xenopus laevis oocyte) in which OR are easily expressed in large amount but whose cellular characteristics are far from neurons in which OR are endogenously expressed