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In comparison, retatrutide also occupies glucagon receptors (GCGR), along with GLP-1 (GLP-1R) and GIP receptors (GIPR)

GLP-1 receptor agonists work through several mechanisms: they enhance insulin secretion when blood glucose levels are elevated, suppress glucagon release (which reduces glucose production by the liver), slow gastric emptying, and promote satiety through effects on appetite centres in the brain

Consult a healthcare provider for more information about potential drug interactions

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