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It occupies a scientifically legitimate space between those extremes: a peptide with a plausible endogenous origin, a well-characterized set of molecular targets, and an unusually consistent preclinical record across diverse injury models and species

Advanced Interventional Musculoskeletal Treatments : Image-guided procedures for complex pain, spinal conditions, and soft tissue injuries

[DOI] [PMC free article] [PubMed] [Google Scholar] 38.Karve I.P., Taylor J.M., Crack P.J

Animal studies and early human data suggest MOTS-c can improve endurance and promote fat loss by activating AMPK (a key metabolic switch)