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Depression in diabetes: have we been missing something important

Individuals with type 2 diabetes have higher rates of osteoarthritis, and obesity itself is a major risk factor for joint disease

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In contrast, more than 80% of those starting SGLT2 or insulin added another medication

In another study, researchers discovered that tirzepatide treatment, when combined with a decrease in circulating levels of branched-chain amino (BCAA) and keto (BCKA) acid metabolites linked to the development of systemic insulin resistance (IR) and T2DM improves insulin sensitivity in obese mice and humans with T2DM [82]