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Swisher SG , Moughan J, Komaki RU, Ajani JA, Wu TT, Hofstetter WL, Konski AA, Willett CG

However, it may be possible to minimize these side effects by initiating treatment with a lower dose and gradually increasing it over time

10.1016/j.pbb.2007.12.018 Pharmacol

Using human or animal-derived chondrocytes or cartilage tissue blocks under simulated intra-articular close-range irradiation conditions, studies demonstrate that PBM at specific parameters can circumvent tissue attenuation associated with transcutaneous irradiation

Clinical monitoring and patient education should include: Symptom recognition : Educate patients about kidney stone symptoms (severe flank or abdominal pain, hematuria, nausea, urinary urgency) and the importance of prompt medical evaluation