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Similarly, specific inhibitors of the cancer protein myoferlin and WJ460 can trigger cell cycle arrest in the G2/M phase and upregulate mitophagy-related genes in PDAC cells, thereby leading to cell death due to excessive Fe 2+ and ROS levels [118]

Neurobiology of Aging, 134, 45-58

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Amlodipine and valsartan was also evaluated for safety in a 6-week, double-blind, active-controlled trial of 130 hypertensive patients with severe hypertension (mean baseline BP of 171/113 mmHg)

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