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This is also suggested by the fact that H 2 S production was decreased 24 h after treatment with 9-methylstreptimidone, 8-hydroxy verrucarin A, chrysomycin and daunorubicin, whereas the level of CBS protein was not reduced before 48 h of treatment

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Hata S, Saito H, Kakiuchi T, et al (2023) Brain p3Alc peptide restores neuronal viability impaired by Alzheimers amyloid peptide

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An ASO modified with LNA, ISTH0047, was designed to specifically decrease TGF-2 mRNA and protein, while sparing TGF-1 and TGF-3, demonstrating notable anticancer efficacy in preclinical animals