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Early human studies demonstrated sustained, dose-dependent increases in growth hormone and IGF-1 following CJC-1295 administration

www.sciencedirect.com , Inflammation , vol

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1 Remove PT-141 vial from refrigeration and allow to reach room temperature (1520 minutes) 2 Clean vial top with alcohol swab and allow to air dry completely 3 Using a sterile syringe, draw the calculated volume of bacteriostatic water (BAC water) 4 Inject BAC water slowly down the side of the vial do not aim directly at the powder 5 Gently swirl in circular motions DO NOT shake vigorously as this degrades the peptide 6 Allow 23 minutes for full dissolution solution should be clear and colorless 7 Draw calculated dose into an insulin syringe for subcutaneous injection 8 Inject into abdomen, thigh, or upper arm

Aging is associated with progressive decline in GH and IGF-1 levels - by age 60, many individuals have GH secretion that is 50-70% lower than peak young adult levels, a phenomenon sometimes called somatopause