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GLP-1 physiology informs the pharmacotherapy of obesity

Unlike the naturally occurring GLP-1 hormonewhich breaks down rapidly and has a short duration of actionOzempics semaglutide formulation has been engineered for prolonged activity

Efficacy and Safety of Once-Weekly Semaglutide Versus Exenatide ER in Subjects With Type 2 Diabetes (SUSTAIN 3): A 56-Week, Open-Label, Randomized Clinical Trial

If a research protocol calls for 12 mg weekly dosing (as used in the Phase 2 trial), a 40 mg vial provides approximately 3.3 weeks of material, whereas a 30 mg vial provides 2.5 weeks

Ozempic is a medication that mimics the effects of GLP-1 to promote weight loss by decreasing hunger and improving satiety