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These include: Nausea (the most common complaint, particularly in the first few weeks) Vomiting Diarrhoea or constipation Decreased appetite (which, while therapeutically desirable, can occasionally be excessive) Abdominal discomfort or bloating Injection-site reactions (such as redness, itching, or mild swelling at the injection site) Headache, dizziness, and fatigue , particularly during early treatment These effects are generally dose-dependent and tend to diminish as the body adjusts to the medication

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95% CI, 1.231.52) [64]

When patients start semaglutide, the most common question after will it work? is: How long will I need to take this? It is an important question and the answer is more nuanced than most online sources let on

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