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Biological or pharmacodynamic half-life the duration of measurable biological effect can differ substantially

In the 1980s, Luckey expanded the scope of hormesis research from chemical toxins to physical factors by proposing the concept of radiation hormesis 5

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Firstly, the Xc system (solute carrier family 7 member 11 and family 3 member 2 (SLC7A11 and SLC3A2)) is responsible for taking up cystine to generate the substrate cysteine for the synthesis of GSH and is also involved in the formation of the GPX4 catalytic unit