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B12 is water soluble, which means B12 doesnt build up in your system once youre at the appropriate amount for your body you will just eliminate any extra, so theres very little risk of an overdose

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Zepbound (tirzepatide) is an FDA-approved medication for chronic weight management that carries a Boxed Warning about thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)