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Alternative lengthening of telomeres is characterised by reduced compaction of telomeric chromatin

Perhaps most amazingly, the mices behavior changed, too frail mice seemed to grow younger and began to explore, exercise, and respond to physical stimuli just like healthy young mice did

Bergknut N, Rutges JP, Kranenburg HJ, Smolders LA, Hagman R, Smidt HJ, Lagerstedt AS, Penning LC, Voorhout G, Hazewinkel HA, Grinwis GC, Creemers LB, Meij BP, Dhert WJ: The dog as an animal model for intervertebral disc degeneration

PubMed PMID 29998800 BPC 157 and angiogenic growth-factor context

Age is actually one reason peptides may be particularly relevant