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GLP-1 agonists like Ozempic and Wegovy also have effects on the brain, specifically on brain areas associated with reward and appetite regulation

Even without GLP-1s, individuals who have struggled with purging or vomiting behaviors are prone to relapse if they develop a sickness where theyre vomiting, says Smith

On a GLP1 medication with reduced appetite, hitting that target requires deliberate planning

The time food is in the stomach is longer

By understanding your genetic predisposition to GLP-1 sensitivity and peptide pathway function, PlexusDx-affiliated clinicians can tailor your starting dose, escalation schedule, and medication choice to minimize uncomfortable transitions