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The proposed mechanisms are multiple and interconnected, reflecting the broad biological footprint of copper-dependent biology in mammalian tissues

Courant T, Roullin VG, Cadiou C, Callewaert M, Andry MC, Portefaix C, Hoeffel C, de Goltstein MC, Port M, Laurent S, Vander Elst L, Muller R, Molinari M, Chuburu F (2012) Hydrogels incorporating GdDOTA: towards highly efficient dual T1/T2 MRI contrast agents

What comes before: Cleanser, Toner, Essence, Serum