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Chemokines that contain the N-terminal motif preferred by DPP4 could serve as substrates for the enzyme, however, data demonstrates that not all chemokines that harbor the motif are acted upon by DPP4 in vivo

Reduced concentrations of N-acetyl aspartate and total creatine in the basal ganglia are markers of neuronal loss and impaired energy metabolism, which correlate with cognitive dysfunction and motor deficits ( Behavioral assessments aligned closely with these imaging findings, offering a clinical perspective on the neurological damage caused by METH abuse

6 New approaches in melasma pharmacotherapy Various adverse drug reactions are associated with systemic treatment and also numerous challenges are existing regarding the skin penetration and clinical efficacy of the topical conventional formulations that are considered in melasma management

Upregulation of NCOA4 significantly elevates intracellular iron levels, further promoting lipid peroxidation and ferroptosis (Masaldan et al., 2018)

ISBN 9780121528232