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In summary, VNS technology holds promise to break through the limitations of traditional PD treatments through mechanism-driven targeted interventions and clinically adaptable technological empowerment, ultimately achieving a paradigm shift from symptom control to disease modification. Statements Author contributions LY: Writing review & editing, Writing original draft

2019), we investigated the effects of its siRNA-based knockdown on glutathione levels

doi: 10.1371/journal.pone.0053657 17 KernJ

HSC70 coordinates COP9 signalosome and SCF ubiquitin ligase activity to enable a prompt stress response

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