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The first FDA-approved oral GLP-1 medication as part of weight management care was Wegovy (oral semaglutide), which also has an injectable version

It acts on: The brain - reduces hunger The stomach - slows emptying The pancreas - improves insulin response Clinical effects include significant appetite suppression , reduced cravings, improved glycemic control, and increased fat loss

The peptides effects on insulin response have been documented in research, with studies showing that IGF1 LR3 can improve insulin response in insulin-resistant models

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