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While the mechanisms by which etomoxir enhances ERAD remain under investigation, these results provide a separate line of evidence that inhibiting -oxidation improves ER homeostasis, perhaps by affecting misfolded protein clearance

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BV binding data were fitted to the tight binding equation (Eq

The analysis of protein-bound thiocyanate in plasma of smokers and non-smokers as a marker of cyanide exposure

Interestingly, coeliac patients also display heightened production of RF at mucosal sites in their GI tract, specifically the jejunum, implying that the immunogenic response generated subsequent to gluten exposure may contribute towards RF synthesis and downstream RA pathogenesis (Hllgren et al