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Additionally, the drugs effects on systemic inflammation and vascular endothelial function may create conditions favoring ischemic events in the posterior ciliary arteries supplying the optic nerve
Leptin, visfatin, and resistin contribute to inflammation, while adiponectin (especially its low molecular weight isoform), has anti-inflammatory effects
Semaglutide may indirectly influence hormone metabolism through weight loss and improved insulin sensitivity, but exogenous testosterone therapy maintains levels independently
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