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Protective role of sirtuin3 (SIRT3) in oxidative stress mediated by hepatitis B virus X protein expression

Liver disease also causes brain issues such as changes in mood and personality

Subsequently, non-enzymatic self-oxidation occurs with molecular oxygen under the catalysis of the Fenton reaction, which is initiated by iron and H 2 O 2 to produce phospholipid peroxyl radicals (PLOO), which are generated by removing hydrogen from another PUFA to generate PLOOH ( Figure 1A )

Initiation of cell death occurs as an early event and progressively increases during the disease course