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others include ETASU (Elements to Assure Safe Use) requiring prescriber certification, patient enrollment in registries, and dispensing only through certified pharmacies

Conversely, internationally, Perjeta experienced continued growth, partly because Phesgo had not yet been launched or reimbursed in some major markets, resulting in a relatively lower impact from patient conversion

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Fatigue is another common early symptom, as healthy kidneys are responsible for filtering waste from the blood and producing erythropoietin, a hormone that supports red blood cell production