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Hypertension is the most common preventable risk factor for CVDs (including coronary heart disease, heart failure, stroke, myocardial infarction, atrial fibrillation, and peripheral artery disease), chronic kidney disease, and cognitive impairment, and also the main single factor for deaths and disability worldwide (133)

2018;1:e186076

In this state, activating SIRT1 may reduce microglia activation and the development of neuroinflammation through its anti-inflammatory effect (He et al

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Early medical assessment is important because ED can be an early indicator of underlying health conditions, particularly cardiovascular disease, diabetes, or hormonal imbalances