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4.1 Absorption into plasma/serum and concentration profiles In a first pharmacokinetic study, eleven healthy volunteers ingested 300 mg Pycnogenol as a single dose and five volunteers received multiple doses of 200 mg Pycnogenol over 5 days (32)

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Ameliorative effect of LC on TMX-induced caspase-3 and GFAP activation The levels of caspase-3 and GFAP expression were measured in the experimental groups to investigate whether LC has anti-apoptotic and anti-astrogliosis effects in the brain

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