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Animals underwent 15 min of global cerebral ischemia, and changes in Glu/GABA/Gln ratios in the hippocampus, cortex, and cerebellum were assessed at 3 h, 24 h, and 72 h post-reperfusion using high-resolution NMR

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"I cannot say we had a clear vision of where we were going, but we had started with the notion that we could block carcinogenesis if we could isolate these substances," Talalay told Johns Hopkins Magazine in 2008

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