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People experiencing significant fatigue on GLP-1 medications who have already addressed basic factors like hydration, protein intake, and electrolytes may find that levocarnitine helps by improving mitochondrial energy production from fat stores

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The reduced appetite and smaller portion sizes make every calorie count towards meeting essential nutrient requirements

Pairing semaglutide with directed diet and strength training minimizes the potential for unintentional lean mass loss and increases the likelihood of maintaining behavioral changes

doi: 10.1016/j.tips.2018.02.007 128 PhensyA.DriskillC.LindquistK.GuoL.JeevakumarV.FowlerB.et al