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Some people tolerate semaglutide better, and others do fine with tirzepatide from the start

27-34 PIONEER 1 PIONEER 1 compared the efficacy and safety of oral semaglutide as monotherapy with placebo in patients with T2DM managed by diet and exercise alone

very slightly soluble in ethanol, acetone, and acetonitrile

Musso G, Sircana A, Saba F, Cassader M, Gambino R (2020) Assessing the risk of ketoacidosis due to sodium-glucose cotransporter (SGLT)-2 inhibitors in patients with type 1 diabetes: a meta-analysis and meta-regression

The pathogenesis of IBD-related bone loss is multifactorial and is related to chronic inflammation, malabsorption, changes in the gut microbiota and glucocorticoid administration