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After a first complete cycle, the most common patient observation is the cellular turnover effect

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All peptides, including fluorescein isothiocyanate (FITC)-labeled p53 TAD (42-57), were manufactured by Dandicure (Ochang, Korea) at a purity of 95%

The therapy effect was ascribed to the counteraction of the congestion of major vessels, and particularly to activation of the rescuing collaterals, i.e., azygos vein direct blood flow delivery

Translational success will require (i) rigorous preclinical-to-clinical pipelines that include long-term toxicity and biodistribution studies, (ii) GMP- compliant manufacturing to ensure reproducibility and scalability, (iii) adaptive trial designs capable of evaluating patient-specific nanotherapies, and (iv) clearer regulatory alignment across FDA/EMA to classify and approve multifunctional nanoplatforms