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GLP-1 medications do not operate in isolationthey act on a complex metabolic network involving: Pancreatic insulin secretion Hepatic glucose output Gastric emptying Central appetite regulation Hormonal signaling Without baseline laboratory evaluation, cliniciansand increasingly, self-directed patientsrisk initiating therapy in a biological context they do not fully understand

These findings validate the experiences of countless patients who feel metabolically "drained" long after the virus has cleared

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