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Research indicates that although semaglutide did not significantly improve hepatic fibrosis, it had positive effects on hepatic steatosis, weight control, and diabetes-related parameters, offering a new therapeutic direction for patients with NASH and compensated cirrhosis ( A study showed that the long-term use of GLP-1RAs could reduce the risk of major adverse liver events (MALE) in patients with type 2 diabetes

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was supported by the German Research Foundation (DFG) KN1148/4-1 and Project-ID 394046635, SFB 1365