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While its an important signaling molecule in small amounts, excess H2S can disrupt various metabolic processes: Glutathione depletion : H2S can release free iron and impair the mitochondrial respiratory chain at complex IV

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It is not a rescue inhaler and should not be used to treat sudden breathing problems

By reducing the number of senescent cells, this approach not only ameliorates physical dysfunction but also decreases mortality hazard and enhances healthspan, providing direct evidence that cellular senescence is a causative factor in age-related diseases (36)