2023 NEJM) showed a 20% reduction in major adverse cardiovascular events on semaglutide in patients with overweight or obesity and established CVD
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Foods to prioritise include: Lean proteins: Chicken, turkey, fish, eggs, legumes, and low-fat dairy help preserve muscle mass and promote satiety Non-starchy vegetables: Leafy greens, broccoli, peppers, courgettes, and cauliflower provide volume and nutrients with minimal calories Whole grains: Oats, brown rice, quinoa, and wholemeal bread offer sustained energy and fibre Healthy fats in moderation: Avocados, nuts, seeds, and olive oil support nutrient absorption and hormone production Fruits: Including bananas, berries, apples, and citrus fruits for vitamins, minerals, and fibre Adequate fluids: Water, herbal teas, and sugar-free beverages to maintain hydration Foods that may worsen side effects or hinder progress: High-fat, greasy foods: Fried items, heavy cream sauces, and fatty meats can exacerbate nausea and delayed gastric emptying Ultra-processed foods: Crisps, biscuits, and ready meals often provide excess calories with poor nutritional value Sugary beverages: Soft drinks, fruit juices, and sweetened coffees add calories without promoting fullness Large portion sizes: Even healthy foods can impede weight loss if consumed in excessive quantities Alcohol: Provides empty calories and may increase appetite whilst lowering inhibitions around food choices During the initial titration period, smaller, lower-fat meals may be better tolerated as your body adjusts to the medication
