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J Phys Chem A

S., Hellstrm, A

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MB is also known for its good tissue penetration, attributed to its low molecular weight and amphiphilic character

Leukocyte and neutrophil mean cell counts remained within normal range between screening, baseline and throughout the pivotal Phase 3 (leukocytes: normal range 4.010.0 109/L mean count at Day 182: 6.6 109/L with garadacimab [n = 39], 6.2 109/L with placebo [n = 24], neutrophils: normal range 2.07.0 109/L, mean count at Day 182: 4.0 109/L with garadacimab, 3.9 109/L with placebo) and OLE studies (At Month 12 [n = 140]: leukocytes: 6.4 109/L