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doi: 10.1007/s00394-014-0706-z 28
Cancer science
I., Jones, T
Cellular adaptation to hypoxia involves an enhanced glycolytic flux, primarily mediated by HIF-dependent transcriptional upregulation of genes encoding glucose transporters and glycolytic enzymes
Conclusion The multifaceted nature of age-associated cognitive decline calls for complex approaches that address all key factors involved in the development of neurodegenerative disorders such as oxidative stress, neuroinflammation, disrupted bioavailability of copper, impaired circulation, and altered gene expression
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