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It has the ability to increase glutathione peroxidase, a powerful antioxidant in the body

However, the efficacy of GLP-1R agonists to reduce drinking in this subgroup may diverge from those without surgery, as GLP-1 is increased after surgery ( In conclusion, these preclinical and clinical studies point toward the possibility of using GLP-1R agonists to treat patients with addictions, an interaction that should be elucidated in future studies

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Parallel investigations are pairing semaglutide with SGLT2 inhibitors, GIP co-agonists and centrally acting appetite suppressants, all aiming to transcend the ceiling of efficacy achievable through single-pathway modulation