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146,147,148,149 The CRISPR-mediated gene-editing system primarily involves Cas9 and single guide RNA (sgRNA) to introduce DNA double-strand breaks (DSBs) at specific positions in the genome

Reconstituted: 28 C, use within 30 days

The hypothalamic-pituitary-adrenal (HPA) axis is supposed to wind down at night, but chronic stress keeps it firing

Remarkably, the TSS pathway is compensatively activated when the extracellular source of cystine is restricted or under extreme oxidative stress conditions

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