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1These events occurred in less than 1% in placebo-controlled trials, but the incidence of these side effects was between 1% and 2% in all multiple dose studies

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Through this modification, certolizumab achieves a half-life comparable to that of full-length monoclonal antibodies (approximately 13 days) [186]

Its antioxidant and anti-inflammatory effects are thought to contribute to its potential neuroprotective benefits