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Mechanistically, in macrophages, GLP-1RAs directly ameliorate NF-B activation, thereby improving insulin resistance [132]

Because of the limited solubility of JS-K in aqueous media no concentration higher than 50 M was used in the measurements

Incidence of pancreatitis and pancreatic cancer in a randomized controlled multicenter trial (SAVOR-TIMI 53) of the dipeptidyl peptidase-4 inhibitor saxagliptin