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On the opposite hand, previous studies have also suggested that autophagy may protect against cell necroptosis, while its inhibition may activate and potentiate necroptosis (Matsuzawa-Ishimoto et al., 2017
The interaction between iron regulatory elements ( IREs ) and iron regulatory proteins ( IRPs ) ensures that iron is appropriately utilized and stored, further connecting heme metabolism with iron recycling [21, 22]
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At varying time points (0, 2, 5, 15, 30 min), purified Pt GSTF8 (8 M) and GSH (20 M) were added to an aliquot of the equilibration reaction and the resulting mixtures were incubated at 30 C for 30 min at 1200 rpm using a 3 mm shaking diameter before extraction with 2 vol of 75% methanol in H 2 O, 1 mM EDTA, 0.3% hydrochloric acid
